Pirfenidone is a new pyridone analog with broad-spectrum antifibrotic effect, which is able to prevent and reverse fibrosis and scar formation; and the drug also has good efficacy in fibrotic diseases such as renal interstitial fibrosis and hepatic fibrosis; and it has been widely used in renal diseases (focal segmental glomerulosclerosis), hypertrophic cardiomyopathy, adult type I multifocal neurofibromas, adolescent type I multiple neurofibromas and plexiform neurofibromas, diabetes with kidney disease, uterine smooth muscle tumor phase II clinical studies, and so on. Chemicalbook neurofibroma, adolescent type I multiple neurofibroma and plexiform neurofibroma, diabetes mellitus with renal disease, uterine smooth muscle tumors of phase II clinical research, etc. It has been widely used.