Ruxolitinib Intermediate_Anti-Cancer_Senova Technology Co., Ltd.

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/ Home / Product Center / Advance Intermediates / Anti-Cancer /

Ruxolitinib Intermediate

APIs

Anti-Diabetes & Weight Loss Anti-Cancer Series Anti-Virus Series Others

Advance Intermediates

Anti-Diabetes Anti-Cancer Anti-Virus Anti-inflammatory Anti-Psychotic Cardiovascular Diseases Others

Peptides & Amino Acid

Peptides Pharmaceutical Grade Amino Acid Food/Feed Grade Amino Acid

Others

(R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile

CAS

941678-49-5

C17H18N6

306.37

Purity

98%

Indication

Ruxolitinib Intermediate

Description

In November 2011, the U.S. FDA approved ruxolitinib (INCB018424) for the treatment of patients with intermediate or high-risk myelofibrosis. Ruxolitinib is an ATP-competitive inhibitor of JAK1 and JAK2 (IC50's of 3.3±1.2 nM and 2.8±1.2 nM

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