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Apremilast Intermediate

1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine
CAS
253168-94-4
MF
C12H19NO4S
MW
273.35
Purity
98%
Melting point
120 °C
Solubility
Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated), Methanol (Slightly)
Appearance
Solid.White to Off-White
Storage Temp
Keep in dark place,Inert atmosphere,Room temperature
Description

1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine is used in the enantioselective synthesis of Apremilast (A729700) aminosulfone using catalytic asymetric hydrogenation. Apremilast EP Impurity H