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Apremilast Intermediate

N-(1,3-dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide
CAS
6296-53-3
MF
C10H7NO4
MW
205.17
Purity
98%
Melting point
185-186℃
Solubility
Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated), Methanol
Appearance
Solid.Off-White to Pale Yellow
Storage Temp
Inert atmosphere,Room Temperature
Description

3-Acetylaminophthalic Anhydride is used in the synthesis of Apremilast, a potent phosphodiesterase 4 and tumor necrosis Factor-α inhibitor used in the treatment of psoriatic arthritis.