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5-Chlorothiophene-2-carboxylic acid can be used in the synthesis of the following:
rivaroxaban, an oxazolidinone derivative used in the treatment of thromboembolic disorders
5-chloro-4-nitrothiophene-2-carboxylic acid, which can be used in the synthesis of thieno[2,3-b][1,4]thiapezine-5-ones