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/ Home / Product Center / Advance Intermediates / Cardiovascular Diseases /

Riociguat Intermediate

APIs
Anti-Diabetes & Weight Loss Anti-Cancer Series Anti-Virus Series Others

Advance Intermediates
Anti-Diabetes Anti-Cancer Anti-Virus Anti-inflammatory Anti-Psychotic Cardiovascular Diseases Others

Peptides & Amino Acid
Peptides Pharmaceutical Grade Amino Acid Food/Feed Grade Amino Acid

Others
Others
1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide,1- [(2-fluorophenyl)methyl]-,monohydrochloride
CAS
256499-19-1
MF
C14H13ClFN5
MW
305.74
Purity
98%

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Melting point
247-249℃
Solubility
DMSO (Slightly), Methanol (Slightly)
Appearance
White solid
Storage Temp
Inert atmosphere,Room Temperature
Indication
Anti-Thrombotic
Description

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride is a key intermediate in the synthesis of Riociguat, a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension.