1-(4-aminophenyl)-5,6-dihydro-3-(4- morpholinyl)-2(1H)-pyridinone
CAS
1267610-26-3
MF
C15H19N3O2
MW
273.33
Purity
98%
Melting point
>246°C (dec.)
Solubility
Chloroform (Slightly), Methanol (Slightly)
Appearance
Off-White to Pale Beige solid
Storage Temp
under inert gas (nitrogen or Argon) at 2–8 °C
Indication
Anti-Thrombotic
Description

1-?(4-?Aminophenyl)?-?5,?6-?dihydro-?3-?(4-?morpholinyl)?-?2(1H)?-?pyridinone is an intermediate in the synthesis of Apixaban (A726700), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.