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Riociguat Intermediate

1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide,1- [(2-fluorophenyl)methyl]-,monohydrochloride
CAS号
256499-19-1
分子式
C14H13ClFN5
分子量
305.74
纯度
98%
熔点
247-249℃
溶解度
DMSO (Slightly), Methanol (Slightly)
外观
White solid
储存条件
Inert atmosphere,Room Temperature
适应症
Anti-Thrombotic
产品描述

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride is a key intermediate in the synthesis of Riociguat, a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension.