1-(4-aminophenyl)-5,6-dihydro-3-(4- morpholinyl)-2(1H)-pyridinone
CAS号
1267610-26-3
分子式
C15H19N3O2
分子量
273.33
纯度
98%
熔点
>246°C (dec.)
溶解度
Chloroform (Slightly), Methanol (Slightly)
外观
Off-White to Pale Beige solid
储存条件
under inert gas (nitrogen or Argon) at 2–8 °C
适应症
Anti-Thrombotic
产品描述

1-?(4-?Aminophenyl)?-?5,?6-?dihydro-?3-?(4-?morpholinyl)?-?2(1H)?-?pyridinone is an intermediate in the synthesis of Apixaban (A726700), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.